Can I use DNA with Sodium Hyaluronate?
Works well together
DNA and Sodium Hyaluronate are generally compatible and can be layered in the same routine. As always, introduce one new active at a time and watch how your skin responds.
DNAHumectant
- ✓High molecular weight DNA acts as a hydrating film-former on the skin surface, binding water through its phosphate backbone and providing an immediate moisturizing effect
- ✓Low molecular weight/hydrolyzed DNA fractions are absorbed more readily and may participate in cellular recognition processes supporting skin renewal
- ✓Used in premium Korean and European skincare as an intensive hydrating and skin-conditioning active; distinct from medical-grade PDRN (polydeoxyribonucleotide) used in aesthetic injections
- ⚠Typically sourced from salmon milt (salmon sperm) — not vegan; individuals with fish allergy should exercise caution
- ⚠Should not be confused with PDRN (polydeoxyribonucleotide) treatments used in aesthetic medicine — topical cosmetic DNA does not penetrate to the cellular level to function as PDRN does
