Active ingredient

Palmitoyl Heptapeptide-18

A synthetic lipopeptide (palmitic acid conjugated to heptapeptide-18) that binds neurons and inhibits acetylcholine release, producing a topical Botox-like reduction in expression lines.

skin-conditioninganti-agingneuropeptide

Benefits

  • Botox-like neuromuscular-relaxing effect that softens expression lines
  • Works synergistically with Palmitoyl Hexapeptide-52 to potentiate wrinkle-smoothing
  • May help even skin tone and reduce hyperpigmentation

No known watch-fors.

In depth

What it does

A synthetic lipopeptide (palmitic acid conjugated to heptapeptide-18) that binds neurons and inhibits acetylcholine release, producing a topical Botox-like reduction in expression lines. As an active ingredient, it is particularly valued for botox-like neuromuscular-relaxing effect that softens expression lines, works synergistically with palmitoyl hexapeptide-52 to potentiate wrinkle-smoothing, and may help even skin tone and reduce hyperpigmentation.

Skin type guide

Generally well-tolerated across skin types, including sensitive skin. As with any new ingredient, a patch test is always a sensible first step.

How to use it

Apply after cleansing and any toning steps, before moisturiser. Start with a few times per week to assess tolerability before building to daily use.

At a glance
CategoryActive
IrritancyLow
Beginner-friendlyYes
Pregnancy safeYes
In your routine

Generally well-tolerated and easy to layer.

Found in 1 product
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Products with Palmitoyl Heptapeptide-18

Microcurrent Activator Line Smoothing Fix SerumSerum
NuFACE
Microcurrent Activator Line Smoothing Fix Serum