Active ingredient

Palmitoyl Hexapeptide-52

A synthetic lipopeptide that suppresses neuron-to-muscle signal transfer, providing a topical muscle-relaxing effect that reduces the appearance of expression lines.

skin-conditioninganti-agingneuropeptide

Benefits

  • Inhibits acetylcholine release to relax expression-line muscle contractions
  • Potentiates the effect of Palmitoyl Heptapeptide-18 when combined
  • Improves the appearance of skin texture, elasticity, and smoothness

No known watch-fors.

In depth

What it does

A synthetic lipopeptide that suppresses neuron-to-muscle signal transfer, providing a topical muscle-relaxing effect that reduces the appearance of expression lines. As an active ingredient, it is particularly valued for inhibits acetylcholine release to relax expression-line muscle contractions, potentiates the effect of palmitoyl heptapeptide-18 when combined, and improves the appearance of skin texture, elasticity, and smoothness.

Skin type guide

Generally well-tolerated across skin types, including sensitive skin. As with any new ingredient, a patch test is always a sensible first step.

How to use it

Apply after cleansing and any toning steps, before moisturiser. Start with a few times per week to assess tolerability before building to daily use.

At a glance
CategoryActive
IrritancyLow
Beginner-friendlyYes
Pregnancy safeYes
In your routine

Generally well-tolerated and easy to layer.

Found in 1 product
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Products with Palmitoyl Hexapeptide-52

Microcurrent Activator Line Smoothing Fix SerumSerum
NuFACE
Microcurrent Activator Line Smoothing Fix Serum