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Ingredient library / Polyaminopropyl Biguanide
Preservative ingredient

Polyaminopropyl Biguanide

Polyaminopropyl Biguanide (PHMB) is a broad-spectrum antimicrobial preservative polymer used in cosmetics, subject to regulatory scrutiny in the EU due to carcinogenicity and inhalation safety concerns.

Also known as: phmb, polyhexamethylene biguanide, polyhexamethylene biguanide hydrochloride

PreservativeAntimicrobial

Benefits

  • ✓Broad-spectrum antimicrobial preservative effective against bacteria, yeast, and mold
  • ✓Permitted up to 0.1% in non-spray cosmetics per EU Annex V (Regulation 2019/831); sprayable/inhalable products are not permitted

Watch for

  • ⚠EU SCCS has concluded it is not safe for use in all cosmetic products at 0.3%; safety concern especially for spray/inhalation products
  • ⚠Classified as CMR 2 (Carc. 2) under EU regulations
  • ⚠US CIR deems safe at current use levels when formulated to be non-irritating and non-sensitizing
At a glance
CategoryPreservative
IrritancyModerate–high
Beginner-friendlyYes
In your routine

Generally well-tolerated and easy to layer.

Found in 1 product
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Products with Polyaminopropyl Biguanide

Cleanse & Polish Hot Cloth CleanserCleanser
Liz Earle
Cleanse & Polish Hot Cloth Cleanser