Emollient ingredient

Squalene

The unsaturated C30 triterpene precursor to squalane, present in human sebum and plant oils such as olive oil; highly susceptible to peroxidation, which distinguishes it from its stable, fully saturated counterpart squalane.

Also known as: spinacene, supraene

emollientskin conditioningskin replenishing

Benefits

  • Natural component of human sebum (~10–15%) — highly skin-compatible
  • Emollient that softens and smooths skin
  • Supports the skin's surface lipid film
  • Found naturally in olive oil and amaranth seed oil

Watch for

  • Prone to oxidation on exposure to air and UV, forming squalene peroxides — comedogenic and pro-inflammatory byproducts
  • Oxidised form (squalene monohydroperoxide) is more comedogenic than established comedogenic cosmetic ingredients in controlled studies
  • May contribute to acne vulgaris when oxidised on skin surface
  • Not recommended for acne-prone skin unless formulated with antioxidants; squalane (saturated) is preferred for stability

Compatibility

✓ Works well with
+ Tocopherol
At a glance
CategoryEmollient
IrritancyLow–moderate
Beginner-friendlyYes
In your routine

Pairs well with Tocopherol.

Found in 2 products
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Products with Squalene

A-Cica 365 Blemish Calming SerumSerum
Aestura
A-Cica 365 Blemish Calming Serum
Atobarrier 365 CreamMoisturizer
Aestura
Atobarrier 365 Cream