Active ingredient
Tetradecylaminobutyroylvalylaminobutyric Urea Trifluoroacetate
Tetradecylaminobutyroylvalylaminobutyric Urea Trifluoroacetate (Inyline, Lipotec/BASF) is a long-chain lipopeptide derivative that mimics the acetylcholine receptor-blocking activity of waglerin-1, a peptide from the temple pit viper (Tropidolaemus wagleri). By competitively antagonizing the muscular nicotinic acetylcholine receptor (nAChR), it reduces the force of facial muscle contraction and thereby softens dynamic expression wrinkles. Its mechanism complements SNARE-targeting peptides (e.g., Acetyl Hexapeptide-8) and collagen-stimulating signal peptides, making it a frequent component of comprehensive anti-aging peptide ampoules.
Also known as: Inyline, TAUT
muscle-relaxingwrinkle-smoothingskin-conditioninganti-aging
Benefits
- ✓Synthetic peptidomimetic of waglerin-1 (venom of Tropidolaemus wagleri, the temple pit viper) that acts as a competitive antagonist at the muscular nicotinic acetylcholine receptor — reducing voluntary facial muscle contraction to smooth expression lines
- ✓Works at the receptor level to reduce the strength of neuromuscular signals rather than blocking neurotransmitter release (unlike SNARE-targeting peptides such as Argireline), providing a complementary mechanism in multi-peptide anti-aging formulas
- ✓Clinically tested (Lipotec/BASF) to reduce the depth of forehead lines and crow's feet; positioned as a topical, non-injectable alternative to support muscle-relaxing anti-aging results
Watch for
- ⚠Not recommended for use during pregnancy or breastfeeding as a precautionary measure given its neuromuscular mechanism
- ⚠Efficacy is concentration- and formulation-dependent; anti-wrinkle benefit is temporary and requires continued use
Compatibility
✓ Works well with
+ Acetyl Tetrapeptide-2+ Acetyl Hexapeptide-8+ Palmitoyl Tripeptide-5+ Sodium Hyaluronate
