Time-Filler 5-XP Wrinkle Correction Cream

A gold-standard humectant that draws water into the skin.

A desert-grass root extract valued for binding moisture and supporting hydration.

An AHA most often used in small amounts to adjust pH.

Enzymatically hydrolyzed sodium hyaluronate with very low molecular weight for deeper skin penetration and enhanced hydration.

A polysaccharide that binds to skin to provide lasting hydration and a soothing film.

A nucleoside used at low concentrations to help smooth the look of fine lines; a common K-beauty anti-aging active.

An extract of the kangaroo paw flower (Anigozanthos flavidus), a native Australian botanical used in premium cosmetics for its antioxidant and soothing properties.

The sodium salt of lactic acid, a natural component of the skin's NMF used as a humectant and mild pH buffer in moisturizers and toners.

A synthetic dipeptide that acts as a reversible antagonist at muscular nicotinic acetylcholine receptors, reducing repetitive facial muscle contractions to smooth expression lines.

An extract of rock samphire (Crithmum maritimum), a coastal plant rich in antioxidant polyphenols and minerals, used in premium skincare for protective and conditioning benefits.

A simple sugar humectant that draws moisture into the skin and serves as a substrate for skin-microbiome-friendly formulations.

The salt form of hyaluronic acid; penetrates more readily.

Vitamin E; a lipid-soluble antioxidant that also conditions skin.

Pure vitamin C; a potent antioxidant and brightener.

The hydrochloride salt of the essential amino acid lysine, used in cosmetics as a humectant and skin-conditioning agent that also supports collagen production.

A naturally occurring amino acid that acts as a humectant and supports the skin's own moisture-retention system.

A collagen-signalling peptide (the second half of Matrixyl 3000) that prompts skin to rebuild structural proteins, improving firmness over time.

A naturally occurring amino acid used as a humectant that helps maintain skin hydration and supports the NMF.

The hydrochloride salt form of the amino acid histidine, used as a humectant, NMF component, and mild pH buffer in cosmetic formulations.

An essential amino acid used in cosmetics as a humectant that supports the skin's natural moisturizing factor system.

An essential branched-chain amino acid used as a humectant that helps maintain skin hydration as part of the skin's natural moisturizing factor.

An essential amino acid used as a humectant that contributes to the skin's natural moisturizing factor.

An essential amino acid used as a humectant that contributes to skin moisturization, barrier integrity, and surface-level repair.

A signal peptide (part of the Matrixyl 3000 system) that helps reduce inflammatory response and supports collagen production for firmer-looking skin.

An essential aromatic amino acid used in cosmetics as a humectant that contributes to the skin's natural moisturizing factor.

A conditionally essential aromatic amino acid used in cosmetics as a humectant that helps maintain skin hydration.

The simplest amino acid, used as a humectant that supports the skin's natural moisturizing factor.

A naturally occurring amino acid that functions as a humectant and is a component of the skin's natural moisturizing factor.

The synthetic, stable form of vitamin B12, used in cosmetics for its antioxidant and skin-conditioning properties; studies suggest topical B12 can reduce eczema symptoms and support skin barrier recovery.

A tripeptide antioxidant valued in skincare for its skin-brightening and free-radical-scavenging effects.

A naturally occurring amino acid that functions as a humectant and is a component of the skin's natural moisturizing factor.

A naturally occurring amino acid that functions as a humectant and contributes to the skin's natural moisturizing factor.

Nicotinamide Adenine Dinucleotide (NAD+), a critical coenzyme in cellular energy metabolism and DNA repair. Included in Filorga's NCEF complex for its cellular energy-supporting properties. NAD+ is the oxidized form; works alongside NADH in the electron transport chain.

A cyclic amino acid that functions as a humectant and forms part of the skin's natural moisturizing factor.

An essential sulfur-containing amino acid that functions as an antioxidant in cosmetics, helping protect formulas and skin from oxidative damage.

A sulfonic amino acid that functions as a humectant and osmoprotectant, helping skin cells maintain hydration balance under osmotic stress.

A non-proteinogenic amino acid and key component of collagen used in cosmetics as a humectant; its presence in the NMF supports hydration and signals collagen stabilization.

The hydrochloride salt of glucosamine, an amino sugar. In topical skincare, studied for its ability to inhibit tyrosinase-related pigmentation pathways and stimulate hyaluronic acid production. Often paired with niacinamide for complementary brightening effects.

Coenzyme A (CoA), a critical cofactor in fatty acid metabolism and the citric acid cycle. Topically, it is included in Filorga's comprehensive NCEF complex to replicate the composition of injectable skin-renewing treatments.

The sodium salt of glucuronic acid, a component of hyaluronic acid's molecular backbone. Used as a mild humectant and skin conditioner that supports natural glycosaminoglycan pathways. Included in Filorga's NCEF complex.

An ester of retinol (vitamin A) and acetic acid — the mildest retinoid ester, requiring two enzymatic conversion steps to reach retinoic acid, giving it a gentler profile than retinol.

A naturally occurring cyclohexane polyol (commonly myo-inositol) found in cell membranes, used in cosmetics as a humectant and skin-conditioning agent.

Nicotinic acid, the free acid form of vitamin B3 (distinct from niacinamide/nicotinamide). At cosmetic use concentrations, functions as a skin conditioner and antioxidant. Included in Filorga Time-Filler 5-XP's NCEF complex alongside niacinamide and other B vitamins.

A versatile vitamin B3 derivative with multiple benefits.

The hydrochloride salt form of vitamin B6, with greater water solubility than the free pyridoxine form; used in cosmetics as a skin-conditioning and sebum-regulating agent, commonly found in oily and acne-prone skin formulas.

The calcium salt form of vitamin B5 (pantothenic acid), which is more stable than panthenol and supports fibroblast activity, skin regeneration, and moisturization.

Vitamin B2, a yellow flavin compound and essential coenzyme for cellular energy metabolism and antioxidant defense; used in cosmetics as a skin-conditioning agent and pigment (imparts yellow color at higher concentrations).

The sodium salt of tocopheryl phosphate — a water-soluble vitamin E ester. Highly stable and penetrates the skin well, converting to active tocopherol intracellularly. Used in Naturie's Hatomugi gel as a water-soluble antioxidant.

The hydrochloride salt form of thiamine (vitamin B1), used in cosmetics as a skin-conditioning and antioxidant active; chemically distinct from the free-base Thiamine INCI and provides improved stability and solubility.

Vitamin B9 (pteroylglutamic acid) used in cosmetics as an antioxidant and skin-conditioning agent that supports cellular renewal.