Can I use Broussonetia Kazinoki Root Extract with Tranexamic Acid?
Works well together
Broussonetia Kazinoki Root Extract and Tranexamic Acid are generally compatible and can be layered in the same routine. As always, introduce one new active at a time and watch how your skin responds.
- ✓Prenylated flavonoids (kazinol F, broussochalcone A) are potent tyrosinase inhibitors that reduce melanin synthesis — comparative in vitro studies show stronger tyrosinase inhibition than kojic acid, making this a high-efficacy brightening active for addressing melasma, PIH, and dullness
- ✓Antioxidant activity from the flavonoid-rich extract protects against UV-induced oxidative stress, a key driver of post-inflammatory hyperpigmentation
- ✓Anti-inflammatory properties reduce the inflammatory cascade that triggers excess melanin production after skin stress, complementing the direct tyrosinase inhibition
- ⚠Generally well-tolerated; prenylated flavonoids may have very mild phytoestrogenic activity in vitro, not considered clinically meaningful at cosmetic topical concentrations
