Can I use Centella Asiatica with Trichosanthes Kirilowii Root Extract?
Works well together
Centella Asiatica and Trichosanthes Kirilowii Root Extract are generally compatible and can be layered in the same routine. As always, introduce one new active at a time and watch how your skin responds.
Centella AsiaticaSoothing
- ✓Calms irritation
- ✓Supports barrier repair
- ✓Antioxidant
Trichosanthes Kirilowii Root ExtractHumectant
- ✓High polysaccharide content delivers strong humectant activity, drawing moisture into the skin and improving suppleness
- ✓Sterols and polysaccharide fractions exert anti-inflammatory effects, helping calm irritated or sensitized skin
- ✓Starch-rich, emollient character contributes skin-conditioning and softening properties consistent with its traditional use as a skin treatment in TCM
- ⚠The crude plant root contains trichosanthin, a ribosome-inactivating protein (RIP) with cytotoxic properties when injected — cosmetic-grade aqueous extracts undergo processing that effectively removes this protein; finished products are not expected to carry the RIP hazard
- ⚠Pregnant individuals should avoid as a precaution given the plant's traditional associations, though topical exposure risk from a processed extract is negligible
