The library

Ingredient library

Every ingredient SkinAtlas knows about — all 2161 of them. What each one does, what it works well with, and what to watch for.

192 ingredients in Active — page 1 of 8

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Active
1-Methylhydantoin-2-Imide

A hydantoin derivative used in Korean skincare as a skin-conditioning active, often as part of amino acid / cell-energy complexes. Hydantoin-based compounds are known for their moisture-binding and skin-softening properties. Appears in Cell Fusion C's aquaporin-boosting formulas.

anti-agingskin-conditioningantioxidant
Used in cell-energy complexes; may support skin's cellular energy metabolismSkin-conditioning agent found in targeted anti-aging formulasOften combined with amino acid complexes for synergistic conditioning
+ Adenosine
Active
2-O-Ethyl Ascorbic Acid
3-O-ETHYL ASCORBIC ACID

An ether derivative of L-ascorbic acid in which the 3-OH position is protected by an ethyl group, making it stable in water-based formulas. Converts to Vitamin C inside skin cells. Used widely in Japanese brightening products (Shiseido, Elixir) as a quasi-drug-adjacent brightening active.

antioxidantskin-brighteningcollagen-synthesis
Stable Vitamin C derivative that brightens skin and evens tonePromotes collagen synthesisLess irritating than L-ascorbic acid at equivalent concentration
May cause mild tingling on sensitive skin at high concentrations
+ Niacinamide+ Tocopherol+ Tranexamic Acid
Active
Acanthopanax Senticosus Root Extract
ACANTHOPANAX SENTICOSUS ROOT EXTRACT

An extract from the root of Acanthopanax senticosus (Siberian ginseng / eleuthero), rich in eleutherosides and lignans. Provides adaptogenic, antioxidant, and mild anti-inflammatory benefits in luxury Japanese skincare.

adaptogenicanti-agingsoothing
Eleutherosides support skin cell turnover and resilienceAdaptogenic — protects against environmental stressAntioxidant and anti-inflammatory properties
+ Panax Ginseng Root Extract+ Adenosine
Active
Acetyl Dipeptide-1 Cetyl Ester

A synthetic dipeptide-cetyl ester (trade name Lumiskin/Calmosensine) that modulates the skin's endorphin pathway to deliver soothing and anti-aging benefits.

peptideanti-aging
Mimics the opioid-pathway signal that triggers skin repairMay improve firmness and skin texture
Active
Acetyl Glucosamine

An amino-sugar (a hyaluronic acid building block) that helps fade uneven pigmentation and supports skin hydration. Pairs well with niacinamide for tone.

brighteninghumectant
BrightensEvens toneSupports hydration
+ Niacinamide+ Hyaluronic Acid
Active
Acetyl Glutamine
ACETYL GLUTAMINE

An N-acetylated form of the amino acid glutamine that supports skin barrier function and stimulates hyaluronic acid synthesis in keratinocytes. Used in serums and liposome-based formulas.

skin-conditioningbarrier-supportanti-aging
Supports synthesis of hyaluronic acid and glycosaminoglycansPromotes skin barrier repairReduces fine lines
+ Hyaluronic Acid+ Hydrolyzed Hyaluronic Acid+ Ceramide NG
Active
Acetyl Heptapeptide-4

A synthetic seven-amino-acid peptide (Ac-Glu-Glu-Met-Gln-Arg-Arg-Ala; trade name Fensebiome™) that acts as a microbiome-modulating active, strengthening the skin's barrier and defence against pathogens rather than acting on neuromuscular SNARE pathways.

skin conditioninghumectantmicrobiome supportbarrier support
Supports skin microbiome balance by promoting growth of beneficial bacteriaReinforces the skin's physical and microbial barrier functionReduces sensitivity and irritation in urban/stressed skin
Active
Acetyl Hexanoyl Dipeptide-3 Norleucine
ACETYL HEXANOYL DIPEPTIDE-3 NORLEUCINE

A synthetic dipeptide derivative with a hexanoyl and acetyl modification. Has melanogenesis-inhibiting properties for skin brightening. Used in Ishizawa's urea face cream.

anti-agingskin-brightening
Inhibits melanin synthesis — skin brighteningAnti-aging dipeptide
+ Niacinamide+ Tranexamic Acid
Active
Acetyl Hexapeptide-1

A synthetic hexapeptide (trade name Melitane) that activates the alpha-MSH receptor pathway to stimulate melanin synthesis and support an even skin tone.

peptideanti-aging
Stimulates melanin production to improve uneven toneMarketed for a healthy-glow effect
May worsen hyperpigmentation, melasma, or other conditions of excess pigmentation — acts as an MC1R agonist that actively stimulates melanin synthesis; not appropriate for those prone to dark spots or uneven darkening
Active
Acetyl Hexapeptide-38
ACETYL HEXAPEPTIDE-38

A biomimetic hexapeptide that stimulates lipid accumulation in dermal adipocytes (fat cells). Used in anti-aging products to restore facial volume and firmness. Found in Minon's aging care products.

anti-agingskin-firmingskin-conditioning
Stimulates lipid synthesis in adipocytes — volumizing and plumping effectAnti-aging — counteracts facial volume lossImproves skin firmness
+ Hyaluronic Acid+ Niacinamide
Active
Acetyl Hexapeptide-4

A synthetic six-amino-acid peptide used in premium Korean skincare formulas for its skin-conditioning and anti-aging properties. Distinct from Acetyl Hexapeptide-8 (Argireline) and from Acetyl Heptapeptide-4 (Fensebiome).

peptideskin-conditioninganti-aging
Synthetic hexapeptide with skin-conditioning and anti-aging claimsUsed in barrier-repair and anti-wrinkle formulas
+ Ceramide NP+ Panthenol
Active
Acetyl Octapeptide-3

An 8-amino-acid acetylated peptide (trade name SNAP-8), the extended version of Acetyl Hexapeptide-3. Acts as a neurotransmitter inhibitor that relaxes facial expression muscles, providing a topical anti-wrinkle mechanism similar to botulinum toxin. Used in premium K-beauty peptide ampoules.

anti-agingmuscle-relaxinganti-wrinkle
Inhibits neurotransmitter release at the neuromuscular junction, reducing repeated facial tensionLonger peptide chain than Acetyl Hexapeptide-3 — may offer enhanced efficacyVisibly smooths expression lines with regular use
+ Acetyl Hexapeptide-8+ Palmitoyl Pentapeptide-4+ Copper Tripeptide-1
Active
Acetyl Tetrapeptide-11

A synthetic signaling tetrapeptide that upregulates syndecan-1 and Collagen XVII expression in keratinocytes, supporting skin barrier cohesion and firmness.

peptideanti-agingcell-communicatingskin-conditioning
Stimulates synthesis of syndecan-1 to strengthen cell adhesion and skin barrierPromotes Collagen XVII production to improve skin firmness and elasticitySupports dermal-epidermal junction integrity for a smoother, more cohesive skin texture
Active
Acetyl Tetrapeptide-2

Acetyl Tetrapeptide-2 (ac-KDVY; trade names Peptigravity, Uplevity, Thymulen-4 by Lipotec/BASF) is a biomimetic signal peptide derived from the thymopoietin hormone sequence. Its principal mechanism is upregulation of the elastin assembly pathway — specifically FBLN5 and LOXL1, proteins required to cross-link tropoelastin into mature elastic fibers — alongside collagen I/IV/VI/XIV stimulation and MMP inhibition. Peer-reviewed AFM studies (PMC6208634) confirm dose-dependent increases in keratinocyte cell stiffness and upregulation of ACTN1, ITGB4, and COL17A1. Used at 0.005–2% in serums, ampoules, and eye creams targeting firmness and skin density loss.

skin-firmingskin-conditioningelastin-boostinganti-aging
Signal peptide that upregulates elastin assembly proteins Fibulin-5 (FBLN5) and Lysyl Oxidase-Like 1 (LOXL1), restoring the cross-linking of tropoelastin into functional elastic fibers — the primary mechanism behind its anti-sagging and firming activityStimulates collagen type I, IV, VI, and XIV gene expression in fibroblasts, plus COL17A1 (collagen XVII) in keratinocytes for strengthened dermal-epidermal junction integrityIncreases keratinocyte and fibroblast adhesion to the ECM via focal adhesion pathway proteins (zyxin, integrin, talin), and inhibits MMPs that degrade collagen — providing structural density and resistance to gravity-related tissue laxity
+ Palmitoyl Tripeptide-5+ Copper Tripeptide-1+ Sodium Hyaluronate
Active
Acmella Oleracea Extract

Extract from Acmella oleracea (electric daisy / paracress), a flowering plant native to Brazil and widely used in traditional medicine for its anesthetic properties. Contains spilanthol and related isobutylamide alkaloids that create a tingling sensation and temporarily block sodium channels in sensory nerves and muscle cells. Used in anti-aging serums as a plant-derived peptide alternative for reducing the appearance of expression lines.

anti-wrinkleskin-conditioningsoothing
Spilanthol — the primary bioactive — temporarily inhibits muscle-contraction signals (sodium channel blocker), creating a mild 'Botox-like' expression-line smoothing effectDocumented in clinical studies to reduce wrinkle depth in expression lines (crow's feet, forehead lines) with topical use over timeAnti-inflammatory activity from spilanthol and isobutylamides soothes skin while simultaneously addressing dynamic wrinkles
+ Niacinamide+ Adenosine+ Palmitoyl Tripeptide-1
Active
Adenosine

A nucleoside used at low concentrations to help smooth the look of fine lines; a common K-beauty anti-aging active.

anti-aging
Helps smooth fine linesSoothing
+ Niacinamide+ Hyaluronic Acid
Active
Aesculus Hippocastanum Seed Extract

An extract of horse chestnut seeds rich in escin saponins and flavonoids, used in cosmetics for antioxidant protection, soothing redness, and supporting capillary integrity.

antioxidantsoothingvasoprotective
Reduces visible redness and soothes irritated skinAntioxidant protection via flavonoids and escinHelps strengthen capillaries and reduce puffiness
Contains escin saponins that may cause irritation at high concentrationsPossible sensitivity in Asteraceae-allergic individuals
Active
Albumen Extract

Extract or concentrated protein fraction derived from egg white (albumen). The primary proteins are ovalbumin (~54%), ovotransferrin (~13%), ovomucoid (~11%), and lysozyme (~3.5%). In skincare, the film-forming proteins create a temporary tightening and pore-minimizing effect as they dry on skin. Skinfood's signature ingredient in their Egg White product line. Distinct from 'Egg Extract' (whole egg) and 'Egg Yolk Extract' (lipid-rich fraction).

film-formingskin-conditioningpore-minimizing
Egg white proteins (ovalbumin, ovotransferrin, lysozyme) temporarily tighten and smooth skin on application — the classic pore-minimizing effectRich source of amino acids and proteins that condition skin and support surface repairLysozyme component provides mild antimicrobial activity, making it suitable for blemish-prone skin masks
Egg-derived — individuals with egg allergies should avoid products containing this ingredient
+ Kaolin+ Glycolic Acid+ Niacinamide
Active
Algae Extract
ALGAE EXTRACT

A general term for extract derived from algae (seaweed). May come from red, brown, or green algae species. Contains polysaccharides (alginate, fucoidan, carrageenan), vitamins, and minerals. Used for its hydrating, antioxidant, and skin-conditioning properties.

antioxidanthumectantskin-conditioning
Rich in minerals, vitamins, and polysaccharidesHydrating and antioxidantBroad-spectrum marine bioactives
+ Hyaluronic Acid+ Niacinamide
Active
Aminopropyl Ascorbyl Phosphate

A stable aminopropyl ester of ascorbyl phosphate that acts as a vitamin C pro-drug, converting to ascorbic acid in skin for brightening and antioxidant benefits.

antioxidantbrighteningvitamin-c
Stable, water-soluble vitamin C derivative that brightens and provides antioxidant protectionConverts to ascorbic acid in skinHelps fade hyperpigmentation
Active
Angelica Acutiloba Root Water

Angelica Acutiloba Root Water is a hydrosol or aqueous extract from the roots of Angelica acutiloba (Toki, Japanese angelica), a plant in the Apiaceae family central to traditional Japanese and Korean herbal medicine. The root is a classic ingredient in Oriental medicine for promoting skin clarity and improving complexion. Its aqueous fraction delivers ferulic acid, chlorogenic acid, ligustilide, and related bioactives. Distinct from Angelica dahurica (Bai Zhi, with furanocoumarin phototoxicity concerns) — Angelica acutiloba has a different phytochemical profile.

skin-conditioninganti-inflammatoryskin-brighteningtoning
Aqueous hydrosol of Angelica acutiloba (Japanese angelica, Toki) root delivers water-soluble bioactives including ligustilide, ferulic acid, and chlorogenic acid with brightening and anti-inflammatory propertiesTraditional East Asian herbal use of Toki for skin tone improvement and circulation support is reflected in its inclusion in premium Korean serums as a botanical brightening tonerFerulic acid and chlorogenic acid fractions in the aqueous extract provide antioxidant and mild UV-protective activity
Apiaceae family — potential for contact sensitization in sensitive individuals; distinct from Angelica sinensis (Chinese angelica) and Angelica dahurica (Bai Zhi) — different phytochemical profile and risk
+ Cnidium Officinale Root Water+ Panax Ginseng Root Extract+ Niacinamide
Active
Angelica Archangelica Callus Extract

Callus (plant cell culture) extract from Angelica archangelica root. Used in premium K-beauty anti-aging products; provides a concentrated, standardised source of the plant's bioactive compounds without seasonal variation.

anti-agingantioxidantskin-conditioning
Plant cell culture technology preserves potent bioactive compoundsSupports skin renewal and firmness in anti-aging formulationsAntioxidant protection from angelica phytocomplex
+ Niacinamide+ Adenosine
Active
Angelica Dahurica Root Extract

Angelica Dahurica Root Extract (Bai Zhi / 白芷) is derived from a root in the Apiaceae family deeply embedded in traditional Chinese and Korean medicine for brightening, anti-inflammatory, and antimicrobial activity. Its bioactives include coumarins, furanocoumarins, volatile oils, and polyacetylenes — the furanocoumarins (psoralen, bergapten) are photosensitizing agents that render standard extracts unsuitable for leave-on daytime use without confirmed furanocoumarin removal per SCCS limits.

skin-brighteninganti-inflammatoryskin-conditioningantimicrobial
Coumarins (oxypeucedanin, isoimperatorin, phellopterin) and furanocoumarins contribute to skin-brightening effects by modulating melanin synthesis pathways — a traditional East Asian brightening ingredient with documented depigmenting activityAnti-inflammatory polyacetylenes and volatile oil components help calm irritation and reduce redness, complementing its brightening use in uneven skin tone formulasAntimicrobial activity from its alkaloid and coumarin fraction supports use in formulas targeting congested or acne-prone skin
Contains furanocoumarins (psoralen, bergapten, imperatorin) — these are phototoxic compounds. Topical application followed by UV exposure can cause phototoxic reactions (erythema, hyperpigmentation, blistering). SCCS guidance: bergapten ≤1 ppm in leave-on productsPM-only use is strongly advisable for standard extracts not certified furanocoumarin-free; leave-on daytime use requires confirmed furanocoumarin removal to safe levels
+ Niacinamide+ Dipotassium Glycyrrhizate+ Ferulic Acid
Active
Arbutin

A gentle brightening agent that inhibits pigment formation.

brightening
Fades dark spotsEvens toneLow irritation
+ Niacinamide+ Ascorbic Acid
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