The library

Ingredient library

Every ingredient SkinAtlas knows about — all 2178 of them. What each one does, what it works well with, and what to watch for.

192 ingredients in Active — page 8 of 8

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Active
Tripeptide-1

A short synthetic tripeptide that mimics a collagen fragment, used in anti-aging formulations to support collagen production and skin resilience.

skin-conditioningcollagen-stimulating
Stimulates collagen synthesisSupports skin firmness and elasticityMay help reduce fine lines with continued use
Active
Tripeptide-10 Citrulline

A synthetic tripeptide incorporating citrulline; targets the extracellular matrix to improve skin firmness and elasticity by supporting fibulin-7-mediated collagen organization.

anti-agingpeptideskin-firming
Citrulline-containing tripeptide that helps maintain skin firmness by supporting collagen network integrityWorks by binding to fibulin-7, which helps organize the extracellular matrix
+ Copper Tripeptide-1+ Acetyl Hexapeptide-8
Active
Tripeptide-2

A synthetic tripeptide included in multi-peptide anti-aging complexes. Tripeptide-2 has been researched for anti-senescence activity — inhibiting proteins associated with cellular aging — complementing the matrix-building and neuromodulating effects of other peptides in pore-refining ampoule formulas.

anti-agingskin-firminganti-senescence
May reduce skin senescence markers and support cellular renewalWorks synergistically with other peptides to improve skin tone and firmnessWell-tolerated in sensitive-skin formulas
+ Tripeptide-1+ Copper Tripeptide-1+ Palmitoyl Pentapeptide-4
Active
Tripeptide-3

A short synthetic tripeptide used in prestige anti-aging ampoules. Tripeptide-3 exerts its effects via neuromodulating pathways, complementing other anti-wrinkle peptides such as Acetyl Hexapeptide-8 and Palmitoyl Pentapeptide-4 in multi-peptide complexes targeting expression lines and skin firmness.

anti-agingskin-firmingmuscle-relaxing
Neurotransmitter-inhibiting mechanism may reduce the appearance of expression linesSynergistic with other peptides in multi-peptide anti-aging complexesLightweight, well-tolerated synthetic peptide
+ Acetyl Hexapeptide-8+ Palmitoyl Pentapeptide-4+ Copper Tripeptide-1
Active
Tripeptide-32

A synthetic tripeptide (Pro-Ser-Thr) marketed as Chronolux, used in anti-aging formulations for its skin-conditioning properties and claimed circadian rhythm-modulating activity.

skin-conditioninganti-aging
Skin-conditioning and hydratingClaimed to modulate skin's circadian rhythm for cellular repairMay enhance resistance to environmental stressors
Claims about circadian activation are largely manufacturer-based; limited independent peer-reviewed evidence
Active
Trisodium Ascorbyl Palmitate Phosphate

A stable amphiphilic vitamin C derivative (combination of ascorbic acid, palmitic acid, and phosphoric acid) that delivers antioxidant and brightening benefits while resisting oxidative degradation.

antioxidantskin-conditioningbrightening
Stable, water-soluble vitamin C derivative resistant to oxidationAntioxidant protection and brightening at low concentrations (0.5–2%)May reduce appearance of fine lines at higher concentrations (2–5%)
Generally considered safe; potential mild irritation at high concentrations in sensitive skin
Active
Triticum Aestivum Seed Extract

An extract from the seeds of Triticum aestivum (common wheat) containing phytosterols, lipids, and antioxidant compounds that condition and support the skin barrier.

skin-conditioningantioxidantmoisturizing
Rich in phytosterols, ceramide-like lipids, and antioxidants that support the skin barrierMoisturizing and skin-softeningAnti-aging properties from wheat peptides and phytosterols
May cause reactions in those with wheat allergy — patch test recommended
Active
Triticum Vulgare Sprout Extract

Extract from sprouted Triticum vulgare (wheat) grains. Germination increases concentrations of antioxidants and phytochemicals, particularly ferulic acid and superoxide dismutase precursors.

antioxidantskin-conditioningbrightening
Sprouted wheat extract rich in growth factors, superoxide dismutase, and ferulic acidAntioxidant protection and skin-conditioning; higher bioactive content than non-sprouted wheat extracts
Individuals with severe wheat allergies should exercise caution, though topical exposure differs from ingestion
Active
Undaria Pinnatifida Extract

An extract from Undaria pinnatifida (wakame), an edible brown seaweed rich in fucoidans, polyphenols, and minerals, used as a standalone active ingredient for antioxidant, hydrating, and skin-conditioning benefits.

antioxidantskin-conditioninghydratingsoothing
delivers fucoidan for hydration and barrier supportprovides antioxidant protectionsoothes and calms skin
Active
Velvet Extract

Extract derived from pre-ossified deer antler (velvet antler), the fastest-growing mammalian tissue known. Contains collagen, glycosaminoglycans, IGF-1, EGF, and other growth factors. Enzymatically digested velvet antler peptides have been shown to accelerate healing, reduce scar formation, and improve collagen fiber organization via TGF-β/Smad2 pathway modulation. Used in K-beauty essences for anti-aging and matrix-nourishing properties.

skin-conditioningcollagen-stimulatinganti-inflammatoryantioxidant
Supports skin firmness and elasticity through collagen precursors, proteoglycans, and growth factor activity including IGF-1 and EGFAccelerates wound repair and reduces scarring by modulating TGF-β signaling and rebalancing collagen I/III ratiosProvides antioxidant protection by upregulating NRF-2 and HO-1 pathways in skin cells
Animal-derived ingredient: not suitable for vegan or cruelty-free routines; harvesting practices varyPossible allergic reactions in individuals with mammal protein hypersensitivity
+ Adenosine+ Sodium Hyaluronate+ Niacinamide
Active
Yeast Extract

A complex mixture of proteins, peptides, amino acids, vitamins, and polysaccharides derived from Saccharomyces cerevisiae yeast, used as a skin-conditioning and protecting active.

Skin ConditioningSkin Protecting
Provides skin-conditioning and skin-protecting effectsSupplies nutrients and antioxidants that support collagen production and skin elasticityHelps reduce inflammation and supports skin barrier function
Generally considered safe; CIR assessment found yeast-derived ingredients safe for cosmetic use at reported concentrations
Active
Yeast Ferment Extract

A fermented extract of Saccharomyces cerevisiae (yeast) containing fermentation-derived amino acids, vitamins, and bioactives; the key brightening active in Missha Time Revolution First Essence, distinct from plain yeast extract or specific filtrate forms.

skin-conditioningbrighteningbarrier-supporthumectant
Provides amino acids, B vitamins, and beta-glucans from fermentationBrightens and evens skin toneSupports skin barrier function
Fermented ingredients may not suit highly reactive skin
Active
Yeast Polypeptides

Polypeptides (short-to-medium chain protein fragments) derived from Saccharomyces cerevisiae yeast, used as film-forming and skin-conditioning agents in premium formulas.

Skin conditioningFilm formingMoisturizing
Provides film-forming moisture retentionConditions skin with yeast-derived peptidesSupports skin texture and suppleness
Active
Yeast/Cherry Blossom Ferment Filtrate
SACCHAROMYCES/PRUNUS SERRULATA JUICE FERMENT FILTRATE

A fermentation filtrate produced by culturing yeast with cherry blossom (Prunus serrulata / sakura) juice. Used in premium Japanese skincare for brightening and skin-conditioning properties.

skin-conditioningantioxidantbrightening
Brightening and antioxidant effects from fermented cherry blossomImproves skin texture and radiancePremium Japanese botanical active
+ Niacinamide+ Tranexamic Acid
Active
sh-Decapeptide-7

sh-Decapeptide-7 is a recombinant human decapeptide produced synthetically to be identical to an endogenous neuropeptide sequence. It belongs to the enkephalin/neuropeptide family and functions as a skin-protecting and anti-irritant active, modulating the response to cutaneous stressors. Used as part of multi-factor growth factor complexes in K-beauty anti-aging formulas (cream, serum), typically alongside other sh- peptides such as sh-Octapeptide-4 and sh-Polypeptide-7.

skin-protectingantioxidantanti-irritantskin-conditioning
Recombinant human decapeptide (10 amino acids) from the neuropeptide/enkephalin family that modulates the skin's response to thermal, chemical, and mechanical irritants — reducing redness and reactivity in sensitized skinAntioxidant activity helps neutralize reactive oxygen species generated by environmental stressors, contributing to overall skin protectionWorks synergistically with other sh- growth factor peptides (sh-Octapeptide-4, sh-Oligopeptide-9) as part of a multi-peptide growth factor complex for skin rejuvenation
As with other recombinant human growth factor peptides, there is a theoretical concern about topical growth factors at high concentrations in individuals with active skin malignancies; not demonstrated as a risk at cosmetic concentrations in standard use
+ sh-Octapeptide-4+ sh-Oligopeptide-9+ sh-Pentapeptide-19
Active
sh-Octapeptide-4

sh-Octapeptide-4 (Neuropeptide-1; trade name SpecPed Sh-O4P by Spec-Chem Industry Inc) is a recombinant human octapeptide produced synthetically to be identical to Leu-Enkephalin, an endogenous opioid neuropeptide. In cosmetics, it functions primarily as an anti-seborrheic and skin-protecting active — modulating sebum output and reducing cutaneous oxidative stress. Its barrier-conditioning and chelating properties complement its neuropeptide-driven activity. Used in multi-peptide anti-aging and skin-balancing formulas.

skin-protectingantioxidantanti-seborrheicbarrier-strengtheningskin-conditioning
Synthetic analogue of Leu-Enkephalin (leucine-enkephalin, an endogenous opioid neuropeptide) that modulates sebum production and reduces excess seborrhea — making it particularly relevant for oily, combination, and congestion-prone skin typesAntioxidant and chelating activity helps protect skin cells against oxidative stress and metal-ion catalyzed free radical damageBarrier-strengthening effect via skin conditioning; produced by Spec-Chem Industry Inc under the trade name SpecPed Sh-O4P
As with other recombinant human peptides, a theoretical growth factor concern applies in specific disease contexts; not demonstrated as a risk at normal cosmetic concentrations
+ sh-Decapeptide-7+ sh-Oligopeptide-9+ sh-Pentapeptide-19
Active
sh-Oligopeptide-1

A synthetic recombinant analog of human Epidermal Growth Factor (EGF) comprising 53 amino acids, used in K-beauty actives to support skin repair, regeneration, and fibroblast activity.

growth-factorregenerativeanti-aging
Promotes skin repair and cellular regenerationSupports fibroblast proliferationMay help smooth the look of fine lines over time
Long-term safety data for topical use is limitedTopical penetration through intact stratum corneum is debated — delivery method impacts efficacy
Active
sh-Oligopeptide-2

A synthetic recombinant analog of human Insulin-like Growth Factor-1 (IGF-1) used in K-beauty anti-aging formulas to support fibroblast proliferation and extracellular matrix synthesis.

growth-factorregenerativeanti-aging
Supports fibroblast activity and cellular growthPromotes collagen and elastin productionMay help improve firmness
Long-term topical safety data is limitedGrowth factor caution — not recommended near active skin tumors
Active
sh-Oligopeptide-9

sh-Oligopeptide-9 is a recombinant human oligopeptide produced synthetically to be identical to an endogenous protein sequence. EU CosIng and INCI Beauty databases list its cosmetic functions as humectant, skin conditioning, and skin protecting. It appears in multi-factor growth factor cream formulas alongside sh-Decapeptide-7, sh-Octapeptide-4, sh-Pentapeptide-19, and sh-Polypeptide-7 as part of an integrated skin rejuvenation complex.

skin-conditioninghumectantskin-protectinganti-aging
Recombinant human oligopeptide that functions as a skin-conditioning active, supporting moisture retention and surface skin texture in multi-factor growth factor complexesHumectant properties help draw water into the skin, complementing the structural remodeling activity of co-formulated signal peptides and growth factorsUsed as part of a growth factor cocktail in premium K-beauty creams targeting skin rejuvenation, skin softness, and overall luminosity
As with other recombinant human peptides, theoretical growth factor concern in specific disease contexts; not demonstrated as a risk at cosmetic concentrations
+ sh-Decapeptide-7+ sh-Octapeptide-4+ sh-Pentapeptide-19
Active
sh-Pentapeptide-19

sh-Pentapeptide-19 is a recombinant human pentapeptide identical to a 5-amino-acid endogenous enkephalin-related sequence. It functions as a skin-conditioning and anti-aging active, used in multi-peptide growth factor complexes for improved skin elasticity, firmness, and overall skin quality. It may be paired with Tripeptide-7 in formulations as a complementary complex. Used in K-beauty premium moisturizers alongside other sh- growth factor peptides.

skin-conditioninganti-agingfirmingskin-protecting
Recombinant human pentapeptide produced synthetically to be identical to an enkephalin-related 5-amino-acid endogenous sequence — contributes to overall skin conditioning and elasticity improvement in multi-peptide formulasAnti-aging and firming activity through skin protein expression support; often paired with Tripeptide-7 as a complementary complex in growth factor formulationsPart of the enkephalin neuropeptide family that modulates skin cell behavior, supporting skin renewal and reducing the visible signs of aging
Theoretical growth factor concern at high concentrations in disease contexts; not demonstrated as a risk at normal cosmetic use levels
+ sh-Decapeptide-7+ sh-Octapeptide-4+ sh-Oligopeptide-9
Active
sh-Polypeptide-1

A synthetic recombinant analog of human basic Fibroblast Growth Factor (bFGF/FGF2) used in anti-aging formulas to stimulate fibroblasts and support structural protein synthesis.

growth-factorregenerativeanti-aging
Encourages fibroblast proliferationSupports collagen and extracellular matrix synthesisHelps improve firmness and elasticity
Long-term topical safety data is limitedGrowth factor caution — not recommended near active skin tumors
Active
sh-Polypeptide-121

A recombinant (biotech-derived) polypeptide modelled on silk growth factors, used in advanced peptide serums to support skin renewal and collagen synthesis.

skin-conditioninganti-agingpeptide
Recombinant polypeptide that mimics growth factors to support skin firmness and renewalHelps improve skin elasticity and plumpness over time
+ Acetyl Hexapeptide-8+ Copper Tripeptide-1+ Niacinamide
Active
sh-Polypeptide-19

A synthetic recombinant analog of human Transforming Growth Factor-α (TGF-α) that promotes keratinocyte renewal and may help smooth expression lines and support post-treatment recovery.

growth-factorregenerativeanti-aging
Boosts keratinocyte generation and migrationMay reduce the appearance of expression lines and wrinklesSupports post-procedure skin recovery
Long-term topical safety data is limitedGrowth factor caution — not recommended near active skin tumors
Active
sh-Polypeptide-7

sh-Polypeptide-7 is a recombinant human polypeptide produced by fermentation in E. coli, consisting of a single-chain synthetic fusion peptide identical to an endogenous human growth factor sequence. EU CosIng lists its functions as skin protecting and anti-seborrheic. Based on patent literature and the growth factor complex context in which it appears (alongside sh-Oligopeptide-1 in other formulas), it is likely related to the KGF/FGF-7 (keratinocyte growth factor) family. Used in multi-factor K-beauty anti-aging cream formulas.

skin-protectingskin-conditioninganti-seborrheicanti-aging
Recombinant human polypeptide produced by E. coli fermentation — likely a keratinocyte growth factor (KGF/FGF-7) family member that supports keratinocyte proliferation and skin renewalSkin-protecting and anti-seborrheic activity in the context of a multi-factor growth factor complex, contributing to overall skin balance and barrier integrityCombined with other sh- peptides (sh-Decapeptide-7, sh-Octapeptide-4, sh-Oligopeptide-9) as part of a Caregen-type growth factor cocktail targeting comprehensive skin rejuvenation
As with all recombinant human growth factors in topical formulations, a theoretical concern exists regarding use by individuals with active skin malignancies; considered safe at cosmetic concentrations for intact healthy skin
+ sh-Decapeptide-7+ sh-Octapeptide-4+ sh-Oligopeptide-9
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