The library

Ingredient library

Every ingredient SkinAtlas knows about — all 2165 of them. What each one does, what it works well with, and what to watch for.

49 ingredients in Barrier support — page 2 of 3

Barrier support
Fatty Acids

A collective term for free fatty acids found in the skin's stratum corneum lipid matrix. Together with ceramides and cholesterol they form the lamellar bilayer that controls skin barrier function and water retention.

barrier-supportemollient
One of the three key lipids in the skin barrier (with ceramides and cholesterol)Reduce transepidermal water lossReinforce lipid bilayer structure
+ Ceramide NP+ Cholesterol+ Ceramide
Barrier support
Glucosyl Ceramide

A glycosphingolipid and natural ceramide precursor that the skin converts into active ceramides, progressively reinforcing the stratum corneum lipid barrier.

barrier-supportskin-conditioning
Acts as a ceramide precursor to stimulate the skin's natural ceramide regenerationStrengthens the lipid barrier and reduces transepidermal water lossImproves skin hydration and reduces signs of dryness and sensitivity
Barrier support
Glycine Soja (Soybean) Peptide

Glycine Soja (Soybean) Peptide is a hydrolyzed soy protein fraction consisting of small peptides (oligopeptides and amino acids) derived from soybean. The peptide fraction is separated from larger proteins and lipids, providing a concentrated mixture of skin-conditioning small molecules. In cosmetics it functions as a barrier-supportive humectant and skin conditioner, contributing bioactive peptides with potential collagen-stimulating and elasticity-improving activity.

skin-conditioningbarrier-repairhumectant
Soy protein hydrolysate peptide fraction containing small bioactive peptides (2–10 amino acids) with documented skin-conditioning, moisture-retention, and barrier-supportive activitySoy-derived peptides include those with ACE-inhibitory and collagen-stimulating activity in vitro; the cosmetically relevant fraction improves skin elasticity and hydration in short-term use studiesProvides a reservoir of amino acids for natural moisturizing factor replenishment, supporting stratum corneum moisture balance
Soy-derived; individuals with severe soy food allergy should exercise caution with topical application, although the allergenicity of extensively hydrolyzed peptides is substantially lower than intact soy protein
+ Ceramide NP+ Sodium Hyaluronate+ Niacinamide
Barrier support
Glycine Soja (Soybean) Sterols
Glycine Soja Sterols

Phytosterols extracted from soybean that reinforce the skin lipid barrier and condition the skin surface.

barrier-supportemollient
Supports the skin barrier by replenishing phytosterolsSoftens and conditions skinHelps reduce transepidermal water loss
Barrier support
Glycocaffinoglycolipid
GLYCOCAFFINOGLYCOLIPID

A specialized glycolipid containing caffeine moieties. Used in Tunemakers' moisture cream for barrier-supporting and skin-conditioning properties.

barrier-supportskin-conditioning
Ceramide-like barrier supportSkin conditioning
+ Ceramide NP+ Hydrogenated Lecithin
Barrier support
Glycosphingolipids
GLYCOSPHINGOLIPIDS

Glycosphingolipids are sphingolipids with one or more sugar residues. Structural components of the skin's intercellular lipid matrix. Used in Tunemakers' peeling lotion to support barrier function.

barrier-supportskin-conditioning
Integral component of skin barrier lipidsReplenishes intercellular lipidsImproves skin hydration
+ Ceramide NP+ Hydrogenated Lecithin
Barrier support
Hexadecyloxy PG Hydroxyethyl Hexadecanamide

A synthetic ceramide-functional molecule developed by Kao/Curél (trade name: Intactamide). Structurally mimics ceramide NP to intercalate into the stratum corneum lipid bilayer and reinforce the skin barrier.

barrier-supportmoisturizingskin-conditioning
Curél's proprietary pseudo-ceramide (Intactamide) designed to mimic the function of natural ceramides in the skin barrierRestores and maintains the moisture barrier in dry, sensitive, and ceramide-deficient skin
+ Ceramide NP+ Glycerin
Barrier support
Hydrogenated Lysolecithin
HYDROGENATED LYSOLECITHIN

A hydrogenated form of lysolecithin, a phospholipid with one fatty acid chain. Hydrogenation improves oxidative stability. Used as an emulsifier and barrier-supportive ingredient in ceramide-rich and sensitive-skin formulations.

emulsifierbarrier-supportskin-conditioning
Structurally similar to skin lipids — excellent compatibilityHelps repair and reinforce the skin barrierEnhanced skin penetration carrier
+ Hydrogenated Lecithin+ Ceramide NP+ Squalane
Barrier support
Hydrogenated Phosphatidylcholine

A fully saturated form of phosphatidylcholine (lecithin) obtained by hydrogenation of unsaturated bonds, used as a stable emulsifier, skin barrier-supportive lipid, and liposome-forming ingredient in high-end serums and creams.

emollientemulsifierbarrier-support
Enhances skin barrier integrity through phospholipid supplementationExcellent skin affinity and biocompatibilityFunctions as a gentle emulsifier in liposomal delivery systems
Barrier support
Hydrogenated Soybean Phospholipid
HYDROGENATED SOYBEAN PHOSPHOLIPID

A hydrogenated form of soybean-derived phospholipids. Hydrogenation improves oxidative stability while maintaining structural similarity to skin lipids. Used as an emulsifier and barrier-supporting ingredient in premium formulations.

emulsifierbarrier-supportskin-conditioning
Structurally similar to cell membrane phospholipidsImproves skin barrier functionEnhanced penetration and delivery
+ Hydrogenated Lecithin+ Ceramide NP
Barrier support
Hydroxypalmitoyl Sphinganine

A phytosphingosine-derived lipid that supports the skin barrier and helps soothe.

barrier-support
Supports the moisture barrierSoothing
+ Ceramide NP+ Phytosphingosine
Barrier support
Hydroxypropyl Bislauramide MEA

A ceramide-analogue from the SKIN-MIMIC technology with lauroyl (C12) chains on a hydroxypropyl-MEA backbone; used alongside Hydroxypropyl Bispalmitamide MEA in Aestura Atobarrier 365 formulations.

ceramide-analoguebarrier-repairskin-conditioning
Supports barrier lipid structure analogous to ceramidesReduces transepidermal water lossSuitable for sensitive and atopic skin types
Barrier support
Hydroxypropyl Bispalmitamide MEA

A ceramide-like lipid from the SKIN-MIMIC technology combining a hydroxypropyl backbone with two palmitoyl chains and an MEA headgroup, integrating into the skin's intercellular lipid bilayer.

ceramide-analoguebarrier-repairskin-conditioning
Reinforces the skin lipid barrier via ceramide-like structureReduces transepidermal water lossUsed in Aestura Atobarrier 365 for sensitive skin barrier support
Barrier support
Milk Protein Extract

Milk Protein Extract is derived from bovine milk and contains a complex of caseins, whey proteins, lipids, and amino acids. In cosmetics, it functions as a skin-conditioning and barrier-supportive ingredient — the protein hydrolysate fraction provides amino acids and hydrolyzed peptide fragments, while the lipid fraction contributes emollient and barrier-reinforcing activity. Commonly used in anti-aging toners and pads at low concentrations for a combined conditioning and barrier benefit.

skin-conditioningbarrier-repairhumectantemollient
Casein and whey protein fractions provide amino acids, ceramide precursors, and lipids that support barrier integrity and skin conditioningHygroscopic properties of hydrolyzed milk proteins help retain moisture in the stratum corneum, contributing a mild humectant effectBioactive peptides released from milk proteins (particularly whey-derived β-lactoglobulin fragments) may stimulate keratinocyte proliferation and barrier repair
Contains milk-derived proteins — not suitable for individuals with severe milk or casein allergy; topical exposure risk from a cosmetic concentration extract is generally low, but caution advised
+ Ceramide NP+ Panthenol+ Allantoin
Barrier support
Myristoyl Methyl Beta-Alanine (Phytosteryl/Decyltetradecyl)
MYRISTOYL METHYL BETA-ALANINE (PHYTOSTERYL/DECYLTETRADECYL)

A complex amino acid ester of myristic acid and phytosterol/decyltetradecyl alcohol. Forms liquid crystalline structures similar to the skin's intercellular lipid matrix. A barrier-supportive ceramide analogue. Used in Ishizawa's urea eye cream.

barrier-supportemollientskin-conditioning
Liquid crystal-forming — integrates into skin's lamellar structureBarrier repair and moisture retentionCeramide-like lamellar lipid
+ Ceramide NP+ Hydrogenated Lecithin
Barrier support
Myristoyl/Palmitoyl Oxostearamide/Arachamide MEA

A synthetic ceramide-analogue combining myristoyl/palmitoyl fatty chains with oxostearamide/arachamide MEA, designed to replenish ceramide NP-type lipids in the skin barrier; used in Real Barrier formulations.

ceramide-analoguebarrier-repairskin-conditioning
Reinforces the skin lipid barrier by mimicking ceramide NPReduces transepidermal water lossSuitable for sensitive and atopic skin
Barrier support
N-Stearoyl Dihydrosphingosine
N-STEAROYL DIHYDROSPHINGOSINE

A synthetic ceramide analogue — the N-stearoyl amide of dihydrosphingosine. Structurally similar to natural ceramide 2 (Ceramide NS). Directly integrates into the intercellular lipid matrix of the stratum corneum, strengthening the skin barrier. Used in premium Japanese skincare brands.

barrier-supportskin-conditioning
Directly replenishes ceramide-like lipids in the stratum corneumStrengthens skin barrierImproves skin hydration
+ Ceramide NP+ Hydrogenated Lecithin+ Cholesterol
Barrier support
Phosphatidylcholine

A naturally occurring phospholipid (the main component of soy lecithin) that closely mirrors the lipid structure of the skin's own cell membranes, making it highly biocompatible for barrier repair and as a liposomal delivery vehicle.

emulsifierskin-conditioningpenetration-enhancer
Major phospholipid component of the skin's lipid bilayer — directly supports barrier repairActs as a natural emulsifier and enhances delivery of active ingredientsSupports moisture retention and reduces transepidermal water loss
+ Ceramide NP+ Squalane+ Sodium Hyaluronate
Barrier support
Phospholipids

A generic INCI listing for a mixture of phospholipids (phosphatidylcholine, phosphatidylethanolamine, and related compounds) that are structural components of cell membranes, used to reinforce the skin barrier and aid active delivery.

EmulsifierSkin-identical lipidBarrier support
Structurally mimics cell membrane lipidsSupports and repairs skin barrierEnhances penetration of co-formulated actives
Barrier support
Phytosphingosine

A precursor lipid that supports barrier function and has soothing properties.

Supports barrierCalming
Barrier support
Pseudozyma Epicola/Camellia Sinensis Seed Oil Ferment Extract Filtrate

A filtrate from fermenting Camellia sinensis seed oil with Pseudozyma epicola yeast, yielding mannosylerythritol lipid (MEL) glycolipids. MELs have a lamellar structure similar to skin's natural lipids, enabling enhanced penetration and barrier-supportive delivery of fatty acids and antioxidants. Key ingredient in Drunk Elephant Lala Retro Whipped Cream.

skin-conditioningemollientbarrier-repairing
Bioferment produced by culturing the yeast Pseudozyma epicola on green tea (Camellia sinensis) seed oil; generates mannosylerythritol lipids (MELs) — natural glycolipid biosurfactantsMELs mimic cell-membrane phospholipids, supporting skin barrier repair and delivering moisturizing fatty acids in a liposome-like structure
+ Ceramide NP+ Cholesterol+ Sodium Hyaluronate Crosspolymer
Barrier support
Rice Bran Glycosphingolipid
Oryza Sativa (Rice) Bran Glycosphingolipid

A sphingolipid fraction extracted from rice bran that supports barrier function by replenishing skin-identical glycosphingolipids in the stratum corneum.

barrier-supportemollient
Reinforces the skin's lipid barrierSupports moisture retention and barrier integrity
Barrier support
Rice Bran Sphingoglycolipid
RICE BRAN SPHINGOGLYCOLIPID

Sphingoglycolipids (ceramide-like lipids) extracted from rice bran. Structurally similar to skin ceramides, they integrate into the intercellular lipid matrix of the stratum corneum to reinforce the skin barrier. Used in Tunemakers' ceramide essence.

barrier-supportskin-conditioning
Plant-based ceramide analogue from rice branReplenishes skin barrier lipidsImproves moisture retention
+ Ceramide NP+ Hydrogenated Lecithin
Barrier support
Salicyloyl Phytosphingosine

A salicylic acid ester of phytosphingosine that combines sphingolipid barrier-repair activity with soothing and mild anti-aging properties, shown in clinical studies to improve wrinkles and ECM protein levels.

barrier-supportsoothinganti-agingsebum-control
Supports and repairs the skin barrierStimulates collagen and ECM protein productionCalms redness and reduces sensitivity