The library

Ingredient library

Every ingredient SkinAtlas knows about — all 2255 of them. What each one does, what it works well with, and what to watch for.

All 2255 ingredients — page 37 of 94

Other
Heptasodium Hexacarboxymethyl Dipeptide-12

A heptasodium salt of a hexacarboxymethyl-functionalised dipeptide-12, used in cosmetics as a chelating and sequestering agent. It binds metal ions that can interfere with preservative systems and formula stability, functioning similarly to EDTA but as a peptide-derived alternative.

chelatingsequestering
Chelates metal ions (calcium, magnesium, iron) that can deactivate preservatives and other activesImproves formula stability by sequestering hard-water mineralsHelps maintain preservative efficacy
Surfactant
Heptyl Glucoside

A mild alkyl polyglucoside surfactant derived from glucose and heptanol, used in gentle, sulfate-free cleansers and micellar waters for all skin types including sensitive skin.

surfactantcleansingsolubilizer
Extremely mild cleansing action suitable for sensitive skinPlant-derived surfactant with anti-irritant propertiesSolubilizes lipophilic ingredients into water-based formulas
Emollient
Heptyl Undecylenate

An ester emollient derived from undecylenic acid that provides a lightweight, non-greasy feel while softening and smoothing skin.

emollientskin conditioning
Provides silky, smooth texture with non-greasy feelQuick-absorbing emollient that softens and smooths skinNatural alternative to cyclomethicone and mineral oils
Antioxidant
Hesperidin

Hesperidin is a flavanone glycoside found primarily in citrus fruit peel — particularly orange and lemon. It is one of the most studied citrus bioflavonoids, with documented antioxidant, anti-inflammatory, and vascular-protective properties. In cosmetics, hesperidin is used for its antioxidant activity and potential contribution to brightening and anti-aging effects. It is distinct from the semisynthetic Hesperidin Methyl Chalcone, which is more specifically used for capillary strengthening.

antioxidantanti-inflammatoryskin-brightening
Hesperidin is a flavanone glycoside naturally abundant in citrus fruit peel with documented antioxidant, anti-inflammatory, and capillary-protective ('vitamin P') activityIn skin, hesperidin stabilizes collagen by cross-linking collagen fibers and inhibiting MMP-degradation; combined with its radical scavenging activity, this provides a comprehensive anti-aging benefitMethyl hesperidin (a water-soluble derivative) has established skin-brightening activity via tyrosinase inhibition; the glycoside form provides antioxidant and anti-inflammatory benefits primarily
+ Ascorbic Acid+ Tocopherol+ Niacinamide
Barrier support
Hexadecyloxy PG Hydroxyethyl Hexadecanamide

A synthetic ceramide-functional molecule developed by Kao/Curél (trade name: Intactamide). Structurally mimics ceramide NP to intercalate into the stratum corneum lipid bilayer and reinforce the skin barrier.

barrier-supportmoisturizingskin-conditioning
Curél's proprietary pseudo-ceramide (Intactamide) designed to mimic the function of natural ceramides in the skin barrierRestores and maintains the moisture barrier in dry, sensitive, and ceramide-deficient skin
+ Ceramide NP+ Glycerin
Fragrance
Hexamethylindanopyran

A synthetic aromatic compound used as a fragrance ingredient with a clean, sweet, musky, floral, woody odor, restricted in EU cosmetics due to allergenic properties.

perfuming
provides clean, sweet, musky, floral, woody fragrance
fragrance allergeneuropean regulation restricts use
Active
Hexapeptide-2

A six-amino-acid peptide that acts as an alpha-MSH antagonist, blocking one of the key signals that triggers melanin synthesis in melanocytes.

skin-brighteningpeptidemelanogenesis-inhibitor
Competes with alpha-MSH (melanocyte-stimulating hormone) to reduce melanin productionHelps even skin tone and reduce the appearance of dark spots
+ Niacinamide+ Oligopeptide-68
Active
Hexapeptide-9

A synthetic matrikine hexapeptide (Gly-Pro-Gln-Gly-Pro-Gln) that mimics a collagen sequence to stimulate extracellular matrix protein synthesis and support skin regeneration.

activeanti-agingskin-conditioning
Stimulates fibroblasts to increase collagen type I and IV productionEnhances hyaluronic acid synthesis in the dermisImproves skin firmness, elasticity, and texture
Fragrance
Hexyl Cinnamal

A synthetic jasmine-scented aldehyde and one of the 26 EU-regulated fragrance allergens, requiring label disclosure above defined concentration thresholds in cosmetics.

fragrant
Contributes a sweet, jasmine-like floral fragrance note
One of the 26 original EU-regulated fragrance allergens (EU Cosmetics Regulation Annex III); must be labeled above 0.001% in leave-on and 0.01% in rinse-off productsRetained in the expanded EU allergen list under Regulation (EU) 2023/1545 effective July 2026
Emollient
Hexyl Laurate

A lightweight synthetic ester of hexanol and lauric acid used as a dry-feel emollient and solvent that improves the texture and spreadability of serums and creams.

emollientsolvent
Lightweight, non-greasy skin feelImproves spreadability and texture of formulasGood carrier for actives
Active
Hexyl Nicotinate

A hexyl ester of nicotinic acid (niacin) that acts as a mild vasodilator when applied topically, temporarily increasing local blood flow and enhancing penetration of other ingredients.

vasodilatoremollientpenetration-enhancer
Increases local cutaneous blood flow for a healthy glow and improved delivery of activesMild emollient properties
Vasodilatory effect causes temporary redness, warmth, and tingling sensation; may be uncomfortable for sensitive skinLimited safety data for use during pregnancy
Solvent / vehicle
Hexylene Glycol

A branched C6 glycol used as a solvent and mild humectant that improves formula spreadability and ingredient penetration.

solventhumectantpenetration-enhancer
Dissolves and carries activesLight humectancyImproves texture and spreadability
Can be sensitizing at high concentrations; used at low levels in cosmetics
Humectant
Hibiscus Esculentus Extract
HIBISCUS ESCULENTUS FRUIT EXTRACT

Extract from okra (Hibiscus esculentus / Abelmoschus esculentus) fruit. High in mucilaginous polysaccharides that create a moisturizing, film-forming effect on skin. Used for hydration and a plumping skin feel.

humectantskin-conditioningfilm-former
Rich in polysaccharides — provides intense moisturizationFilm-forming and plumping effectSoothing
+ Hyaluronic Acid+ Glycerin
Antioxidant
Hibiscus Sabdariffa Flower Extract

An extract from hibiscus flowers rich in anthocyanins, citric, and malic acids with antioxidant, brightening, and mild exfoliating properties.

antioxidantbrighteningexfoliant
Rich in anthocyanins and organic acids for antioxidant protectionNatural AHA content contributes mild exfoliationHelps brighten and even skin tone
Naturally acidic — high concentrations may cause sensitivity in reactive skin
Antioxidant
Himanthalia Elongata Extract

Extract from Himanthalia elongata (sea spaghetti), a brown algae harvested from Atlantic coasts. Rich in phenolic compounds and fucoidan polysaccharides, providing antioxidant activity and skin-conditioning properties in marine-inspired skincare formulas.

antioxidantskin-conditioning
Brown macroalgae (sea spaghetti) extract rich in polyphenols, sulfated polysaccharides (fucoidan), and mineralsProvides broad-spectrum antioxidant protection and supports the skin's natural defenses against oxidative stress
+ Tocopherol+ Physalis Angulata Extract
Antioxidant
Hippophae Rhamnoides (Sea Buckthorn) Fruit Extract
Hippophae Rhamnoides Fruit Extract

A carotenoid-rich sea buckthorn fruit extract delivering antioxidants and skin-nourishing nutrients.

antioxidantconditioning
Antioxidant protectionRich in carotenoids and vitaminsConditions and nourishes skin
Deep orange color can temporarily stain skin or fabrics
Emollient
Hippophae Rhamnoides Fruit Oil

The pressed oil from sea buckthorn fruit, distinct from a water extract, delivering a highly concentrated source of carotenoids, omega-7 fatty acids, and tocopherols.

emollientantioxidant
Exceptionally rich in carotenoids, fatty acids, and tocopherolsNourishes and conditions skinAntioxidant support
Intense orange-red pigmentation can stain skin and fabrics at high concentrations
Active
Hippophae Rhamnoides Fruit Water

The water fraction obtained from the fruit of sea buckthorn (Hippophae rhamnoides), distinct from the steam-distilled hydrosol (Hippophae Rhamnoides Water) and the lipid-rich fruit oil; used primarily as a solvent and mild skin-conditioning agent in water-based cosmetic formulas.

solventskin-conditioningantioxidant
Aqueous fraction of sea buckthorn (Hippophae rhamnoides) fruit, retaining water-soluble bioactives including flavonoids and organic acidsProvides mild antioxidative and skin-conditioning properties characteristic of sea buckthornSuitable for water-phase formulations where the heavier fruit oil or extract would not be appropriate
Generally well-tolerated; sea buckthorn derivatives may cause reactions in individuals with known plant allergies
Other
Hippophae Rhamnoides Water

The steam distillate (hydrosol) of sea buckthorn (Hippophae rhamnoides), distinct from the fruit extract and seed oil; used for its mild antioxidative and skin-conditioning properties in water-based formulas.

skin-conditioningfragranceflavoring
Steam distillate of sea buckthorn (Hippophae rhamnoides) containing water-soluble volatile compoundsProvides antioxidative, regenerative, and soothing properties characteristic of sea buckthornSkin conditioning with hydrating and calming effects
Humectant
Histidine

A semi-essential amino acid naturally present in the skin's NMF that acts as a humectant and antioxidant to hydrate and protect skin.

humectantamino-acid
Attracts and retains moistureSupports the skin's natural moisturizing factors (NMF)Antioxidant protection
Humectant
Histidine HCl

The hydrochloride salt form of the amino acid histidine, used as a humectant, NMF component, and mild pH buffer in cosmetic formulations.

humectantamino-acidph-adjuster
Attracts and retains moisture as part of the skin's NMFSupports the skin's natural moisturizing factorBuffers formula pH in acidic conditions
UV filter
Homosalate

A classic UVB-absorbing chemical sunscreen filter commonly used to dissolve and stabilize other filters.

uv-filter
Absorbs UVB radiationActs as a solvent for other UV filters
EU SCCS flagged potential endocrine-disruption concerns; EU reduced the permitted concentration to 7.34%
+ Avobenzone+ Octocrylene+ Octisalate
Active
Homosulfamine
HOMOSULFAMINE

A sulfonamide-type antibacterial compound used in Japanese quasi-drug (OTC medicated) skincare products for acne treatment. Has antimicrobial activity against bacteria including Cutibacterium acnes. Used in Meishoku's medicated skin lotion.

antimicrobialanti-acne
Antimicrobial — targets acne-causing bacteriaUsed in Japanese quasi-drug (医薬部外品) acne formulations
Active pharmaceutical ingredient — follow product instructions; avoid overuse
+ Salicylic Acid
Humectant
Honey
Mel

A natural humectant that hydrates, soothes and conditions skin with mild antimicrobial activity.

humectantsoothing
Attracts and binds moistureSoothes and softens skinMild antimicrobial properties
+ Hyaluronic Acid+ Centella Asiatica